COPD: an inhaled corticosteroid-resistant, oral corticosteroid-responsive condition

COPD: an inhaled corticosteroid-resistant, oral corticosteroid-responsive condition.

parking area and inside the Bella Center, with a level of 6.0¡1.7 and 3.0¡0.9 mg?m, respectively. Peak values were 12.5 mg?m and 12.0 mg?m, respectively. However, outside in front of the Bella Center with smokers, mean PM2.5 was 17.8¡7.5 mg?m with a peak of 98.9 mg?m (p,0.03, as compared with inside the venue), which is a step down in AQI. PM2.5 along the motorway was only 4.6¡0.7 mg?m with a p...

Stable COPD: predicting benefit from high-dose inhaled corticosteroid treatment.

The role of inhaled corticosteroids in the management of chronic obstructive pulmonary disease (COPD) remains controversial. The purpose of this study was to evaluate whether sputum eosinophilia (defined as eosinophils > or = 3%) predicts clinical benefit from inhaled corticosteroid treatment in patients with smoking-related clinically stable moderate-to-severe COPD. Forty consecutive patients ...

Inhibition of reactive nitrogen species production in COPD airways: comparison of inhaled corticosteroid and oral theophylline.

BACKGROUND Reactive nitrogen species (RNS) are thought to be one of the important factors in the pathogenesis of chronic obstructive pulmonary disease (COPD). A study was undertaken to examine the effects of theophylline and fluticasone propionate (FP) on RNS production in subjects with COPD. METHODS Sixteen COPD subjects participated in the study. Theophylline (400 mg/day orally) or FP (400 ...

Inhaled corticosteroid and children's growth.

No one ever died because they fell 1 cm short of their potential final height, but many families understandably worry about the side effects of inhaled corticosteroids (ICS), and may stop ICS treatment in consequence. It is important to state at the outset that reduced linear growth in a child with asthma should not uncritically be attributed to ICS, but should rather lead to a critical re-eval...

Inhaled corticosteroid dosage in asthma.